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The initial decrease in testosterone is considered a temporary, adaptive response to rapid weight loss and caloric deficit
That is roughly 1 in 11 people
Moreover, in mice, genetic deletion of GLP-1 receptors enhances ApoB-48 secretion in the absence of changes in gastric emptying (76)
This mechanism can lower your overall calorie intake, and when your body shifts to using stored energy faster than usual, some people experience temporary fatigue
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