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These investigations are performed in non-human or in vitro settings and do not represent established safety or efficacy in humans
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Challenges in studies of GLP-1 and in development of GLP-1R agonists In the era of rapid daily progress in biomedical science, it is surprising that it took almost 20 years from identification of GLP-1 to successful approval of the worlds first clinically utilized GLP-1R agonist
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