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Glucagon-like peptide-1 (GLP-1) is a type of incretin hormone that is secreted by intestinal L-cells in response to a meal

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and for Boc-His(Trt)-OH, the coupling was performed by a HOBt/HBTU/Di the Fmoc-Gly-Wang resin synthesized in Example 2 was used for the synthesis of peptide resin of Semaglutide