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and Novo Nordisk A/S settled a patent lawsuit and validity challenge linked to Novos blockbuster weight-loss and diabetes drugs Ozempic and Wegovy.

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We used version 2 of the Cochrane risk-of-bias tool (ROB 2) to assess the risk of bias, conducted frequentist random-effects network meta-analyses and evaluated confidence in effect estimates utilising the Confidence In Network Meta-Analysis (CINeMA) framework

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A widely prescribed class of weight-loss and diabetes medications may be doing more than improving metabolic health.