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2016;59(Suppl 1):S3645

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We decided to restrict our study to male mice because we have previously shown that juvenile malnourished males display a stronger phenotype than malnourished females [24]

Values presented as percentage of total Adverse events are presented for all participants who were randomised and took at least one dose of treatment, regardless of whether they discontinued * For the T2D trial, this was limited to supraventricular arrhythmias and cardiac conduction disorders ** For the obesity trial these are presented as hepatic disorder / biliary disorder separately NA : Not applicable In the obesity trial, serious adverse events (SAEs) occurred in 4% of participants with retatrutide use overall (06% across groups) vs