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En STEP 1, los pacientes con obesidad sin diabetes perdieron una media del 14,9% del peso corporal a las 68 semanas (vs 2,4% con placebo)

Kim MK, et al

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GLP-1, an incretin hormone, is synthesized in the brainstem, pancreas, and intestines, playing a crucial role in postprandial blood sugar regulation
Back Chaiborn, C (1 Aug 2011) 'Masters of metabolism: Matthias Tschp and Richard DiMarchi', The Journal of Clinical Investigation , 121/8, 2952