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Clinical evidence suggests no major contraindication between GLP-1 agonists and standard HRT regimens (estrogen-progesterone combinations or estrogen-only therapy)

[DOI] [PubMed] [Google Scholar] 160.Sun T., Xu W., Wang J., Wang T., Wang S., Liu K., Liu J

Also as of March 2024, Wegovy was approved to reduce the risk of heart attack or other serious cardiovascular problems in adults with obesity or overweight

I hardly felt it at all

Emerging role of SGLT-2 inhibitors for the treatment of obesity

Most physicians recommend introducing one compound before the other rather than starting both simultaneously
