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Advise patients on the symptoms of hypersensitivity reactions and instruct them to stop taking OZEMPIC and seek medical advice promptly if such symptoms occur [see Warnings and Precautions (5.8)]

Tirzepatide has shown reductions of up to 2.4% , making it slightly more effective for diabetes management

The clinical presentation of hypothyroidism reflects the consequences of a slowed metabolic rate: fatigue, weight gain, cold intolerance, constipation, dry skin, bradycardia, and, in some patients, depression

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Additionally, reduced overall food intake during treatment decreases dietary magnesium consumption

In phase 2 clinical trials, some participants experienced a slight increase in heart rate