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Access and cost are practical hurdles in many settings

Consistency matters more than the clock hour, so pick whichever time you will stick to long-term

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1 Although GLP-1 RAs are considered to have effects on both fasting and prandial glucose control, evidence suggests that the shorter-acting agents (exenatide and liraglutide) have a greater effect on postprandial values compared to the weekly administered GLP-1 RAs

Note urine color as a quick hydration check

Severe and persistent gastrointestinal symptoms can precipitate acute kidney injury, which is the main concern prompting monitoring in high-risk individuals