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Clinicians must carefully evaluate individual patient risk factors, particularly personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2), before prescribing these agents

Along with that, the network meta-analysis demonstrated that the cognition of AD patients could be significantly improved after using anti-diabetic drugs (70)

While the phenomenon has attracted public attention under a memorable nickname, medical experts agree that the underlying changes are best understood as a consequence of significant fat loss rather than a direct side effect unique to any single medication

Patients should report persistent vomiting, severe abdominal pain, or signs of dehydration promptly, as these may compromise immunosuppressant absorption or indicate complications requiring urgent assessment

doi: 10.1016/j.cmet.2025.06.012

Additionally, linagliptin, a xanthine-based drug, emerged from another development pipeline and received approval after significant research efforts