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Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study

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Discuss key efficacy and tolerability data from clinical trials published to date with oral semaglutide

Plasma DPP-4 activity and TG excursion were reduced, and plasma active GLP-1 was increased, in sitagliptin-treated Dpp4 +/+ mice, but sitagliptin had no effect in Dpp4 / mice (Figure 1, B and C, and Supplemental Figure 3, A and B), consistent with the selectivity of sitagliptin for DPP-4 (22)