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Description
Osteoarthritis treatment via the GLP-1mediated gut-joint axis targets intestinal FXR signaling

Oral formulations are projected to grow at a 34.87% CAGR through 2031 as late-stage trials conclude
A similar modification was performed in albiglutide

12 Centrally acting GLP1RAs are capable of crossing the bloodbrain barrier and binding to receptors in limbic and hypothalamic regions involved in appetite regulation, stress response and affective processing

One double-blind, placebo-controlled study showed that GLP-1 can decrease aldosterone secretion in healthy individuals suggesting that GLP-1 can act on blood pressure and the reninangiotensinaldosterone system [93]

Protein shakes designed for GLP-1 users can help when solid food feels challenging during periods of strong appetite suppression
