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CONFLICT OF INTEREST JPHW reports receiving advisory board fees, paid to his institution, from Astellas Pharma, grant support and fees for membership on a data and safety monitoring board, both paid to the University of Liverpool, lecture fees and travel support from AstraZeneca, advisory board fees, paid to his institution, and lecture fees from Boehringer Ingelheim, Napp and Sanofi Pasteur, advisory board fees, paid to his institution, from Eli Lilly, Janssen Global Services, Rhythm and Wilmington Healthcare, lecture fees from Mundipharma, grant support, advisory board fees and fees for serving as an investigator, all paid to the University of Liverpool, and lecture fees from Novo Nordisk and advisory board fees from Takeda Medical Research Foundation

One works from the top down through the brain

Treatment starts at 0.25 mg weekly for four weeks to improve tolerability, then typically increases to 0.5 mg, with further escalation to 1 mg or 2 mg if needed

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While GLP-1 drugs were originally developed to treat diabetes, researchers keep finding new ways for these medications to boost patient outcomes

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