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In cohort studies SGLT2 inhibitors were associated with a two-fold increased risk of EDKA as compared with GLP-1RAs

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Single case reports, pilot studies, animal studies, and literature reviews were excluded

Both Eli Lilly and Novo Nordisk now also offer consumers who lack insurance coverage the option to buy Zepbound and Wegovy, respectively, on direct-to-consumer platforms at a lower cost

Fewer Overdoses and Drug-Related Deaths The study also examined outcomes among the 81,617 participants who already had a substance use disorder
