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Scientists analyzed electronic medical records for more than 73,000 people and found that after 5 years, GLP-1 use was linked to a significantly higher risk of developing osteoporosis, compared to those not taking the medication

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Lixisenatide and exenatide may influence outcomes, too

Epidemiology of chronic complications of diabetes: a global perspective

Lets break it down STUDY DESIGN 245 adults w/ type 2 diabetes + BMI 27 kg/m All on metformin Randomized to: Semaglutide 2 mg Semaglutide 8 mg Semaglutide 16 mg Placebo Fixed titration (no dose flexibility) over 40 weeks KEY RESULTS (Hypothetical Estimand): - - - HbA1c Reduction 2 mg: 1.9% 8 mg: 2.2% 16 mg: 2.4% 16 mg vs