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Considerable expenditure will be necessary for research and development, formulation development, clinical trials, and gaining regulatory approval

Studies of HFrEF patients raised questions about the safety profile of GLP-1RA therapy in this subpopulation

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Pal S, Rao GN, Pal A

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This protective effect is mainly advantageous for type 2 diabetes, where beta cells are still present but not functioning well