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While they do contribute to fluid intake, caffeine has mild diuretic properties and can irritate the bladder lining, which is counterproductive for UTI prevention

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While prescribed PERT products are regulated as medicines, most over-the-counter enzyme supplements are regulated as food supplements in the UK, with less stringent quality controls

The IGF system consists of six IGF binding proteins (IGFBPs) and two growth factors (IGF-1 and IGF-2) along with their cognate insulin growth factor receptors (IGF-1R, IGF-2R) [15]

However, it is impractical to keep patients on the same diet longitudinally, especially because GLP-based therapies alter appetite and food intake