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Their primary mechanisms of action include: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood glucose levels without causing hypoglycaemia when used alone Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production Slowing gastric emptying , which prolongs satiety and reduces appetite Acting on appetite centres in the brain , particularly the hypothalamus, to reduce food intake Most GLP-1 receptor agonists are administered via subcutaneous injection, with dosing frequencies ranging from twice daily to once weekly depending on the specific formulation

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This means avoiding poorly absorbed sugars that can ferment and cause gas (like certain fruits, sweeteners, wheat, and legumes)

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Balance fiber intake : Consider temporary reduction of gas-producing fibers while ensuring adequate intake to prevent constipation, which is common with GLP-1 receptor agonists

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