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Compared with SGLT-2 inhibitor use, GLP-1 receptor agonist use was not associated with an increased risk of pulmonary aspiration (pooled risk ratio 0.98, 95% CI 0.73 to 1.31), although it was associated with a higher risk for discontinuation of endoscopy (1.99, 1.56 to 2.53)

The incretin effect is defined as the higher stimulation of insulin secretion obtained when glucose is administered orally than intravenously, under similar plasma glucose levels