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the tolerable upper limit from supplements alone is 350 mg/day, above which loose stools are the usual result (NIH Office of Dietary Supplements)

Unexpected signals included kidney injury and pancreatic cancer

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6 , 712.e11 (2014)

The human leukocyte antigen (HLA) class II, cytotoxic T lymphocyte antigen-4 (CTLA-4) (on chromosome 2q33), protein tyrosine phosphatase non-receptor type 22 (PTPN22) (1p13), forkhead box P3 (FOXP3) (Xp 11), and interleukin 2 receptor (IL-2R) (10p15) are major genes found to contribute to a joint susceptibility for T1DM and AITD [29,31,32]

That definitely shaped my path and my love for regenerative medicine
