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GLP-1 amidation efficiency along the length of the intestine in mice, rats and pigs and in GLP-1 secreting cell lines

This increases the risk of aspiration (inhalation of stomach contents into the lungs) during general anaesthesia when protective airway reflexes are suppressed

Beyond the prescription: Global observations on the social implications of GLP-1 receptor agonists for weight loss

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This practical support has made split dosing easier to implement but has also drawn criticism from those who argue that compounding pharmacies should not be encouraging unstudied dosing modifications