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Clinical nutrition guidelines recommend that patients on weight loss therapy engage in regular physical activity and consume sufficient protein to help preserve muscle mass

Its not required but is recommended as part of your treatment
10.2337/db11-1029 48 GribbleF

A starting target set 300 calories below estimated maintenance intake

Of that group, 54.6% lost at least 10% of their weight, 36% lost at least 15%, and 18.4% lost 20% or more
