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Officers from the MHRA's Criminal Enforcement Unit (CEU) haveraidedtwo separatepremisesas part of an ongoing investigation into an organised criminal network involved in the manufacture and sale of unlicensedweight lossmedicines.

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New research reveals GLP-1 weight-loss drugs may boost or decrease sexual function, with 52% of users reporting changes in their sex lives, according to recent studies.

However, as DPP4 recognizes other substrates such as chemokines, growth factors and neuropeptides, pleiotropic effects have been observed in patients treated with DPP4i

Purpose of Review This review summarizes the current understanding of the physiologic influence of GLP-1 RAs on gastrointestinal motility, highlights key clinical implications of these effects, and defines areas for future investigation