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In the brain, major GLP-1R-positive regions include the area postrema, ARC, VMH, and the ventrolateral medulla with lower expression in the PVH and NTS [395,396]

They may also indirectly help with blood pressure regulation, though they are not yet FDA-approved for this purpose

Prepare practice workflows for oral GLP-1 management

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They noted, however, that no significant differences with respect to the primary study outcome were found between groups in the modified intention-to-treat population