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For men specifically, several factors make this mechanism particularly relevant

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The medications decrease appetite and suppress hunger cravings by affecting the brains reward systems

After 28 days, potency begins to decline and bacterial contamination risk increases beyond acceptable levels

doi: 10.3390/ijms23020739

These data suggest that GLP-1RAs may have unwanted oncogenic effects on receptor-positive NET subtypes (e.g., duodenal, gastric, and pancreatic NETs) and are less likely to affect NENs lacking the receptor (e.g., thyroid and ileal NETs)
