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Semaglutide is neuroprotective and reduces -Synuclein levels in the chronic MPTP mouse model of Parkinsons disease
We also show that GLP-1 inhibits inflammatory pathways in the LPS-induced RAW264.7 cells
Like Ozempic and others approved for diabetes, Mounjaro was often prescribed off-label to patients for weight loss
Gastric inhibitory polypeptide (GIP) dosedependently stimulates glucagon secretion in healthy human subjects at euglycaemia

Source Reference: Bliddal H, et al "Once-weekly semaglutide in persons with obesity and knee osteoarthritis" N Engl J Med 2024
Neurosci Lett 2003