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It is produced by post-translational processing of preproglucagon, a precursor of many glucagon related peptides

In addition to these common side effects, there are some less common but more serious potential side effects, such as inflammation of the pancreas, gallbladder disease, kidney injury, and blockage of the intestines

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They are typically made by mixing the active ingredient with other ingredients.* People use compounded GLP-1s for a few reasons: There is a shortage of brand-name of GLP-1 medications (like Zepbound and Wegovy)

Both medications cause some lean mass loss, but the ratio of fat loss to lean mass loss appears to favor tirzepatide based on available body composition data from the SURMOUNT trials

doi: 10.2337/db18-0068 89 MallinsonCNBloomSRWarinAPSalmonPRCoxB