do not combine dpp-4 inhibitors with glp-1 receptor agonists guidance Frontiers do not combine dpp-4 inhibitors
Description
In the pancreas, GLP-1RAs enhance insulin secretion and inhibit the release of glucagon, a hormone that induces the breakdown of stored sugars into the bloodstream
J.van der TuinS
This approach can also result in increased production of other hormones produced by L-cells such as oxyntomodulin and peptide YY (PYY), which can enhance the metabolic effects of GLP-1
It may also reduce body weight and strengthen cardiovascular health
Lixisenatide: A New Daily GLP-1 Agonist for Type 2 Diabetes Management
GIP, glucose-dependent insulinotropic polypeptide
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