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GLP-1R activation reduces intake

When it comes to weight loss, its important to recognize that alcohol is a sneaky source of empty (non-nutritious) calories that may hinder progress

Transitioning from compounded tirzepatide to Zepbound or Mounjaro for weight loss is important because Zepbound and Mounjaro are FDA-approved treatments specifically designed to help with weight management

Over the last few years, I have been working really hard to keep y disease in check and when that finally happened, I was left with another issue, fatty liver due to excess medications and weight, forcing my body to struggle

I think the diet advocates need to be aware of GLP-1 success and the GLP-1 mavens need to be aware of the success of diets in RA, OA, SpA, PsA, etc

In clinical trials, retatrutide achieved 24.2% weight loss at 48 weeks versus tirzepatide approximately 21% at 72 weeks, suggesting stronger overall appetite and metabolic effects