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This endogenous GLP-1 enters the bloodstream, reaches the joint, binds to GLP-1 receptors in joint tissue, and protects cartilage

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124 A role for the gastroduodenal peptide CCK has also been suggested in the impaired motility of the gallbladder in people with diabetes, including reduced sensitivity of the gallbladder smooth muscle to plasma CCK and a reduction in CCK receptors in the gallbladder wall
Rasmussen et al., 2021)

Along with this, the market is estimated to grow at a CAGR of around 3.66% during the forecast period, i.e., 2026-32

These findings may explain the reduced responsiveness to GIP observed in individuals with T2DM who may have normal or even increased secretion of GIP
