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Systemic inflammation drives both metabolic dysfunction and neurological pain

Complementary approaches may include: Behavioral therapy or weight management counseling Sleep optimization (79 hours nightly) Stress management techniques Evaluation and treatment of coexisting conditions (insulin resistance, sleep apnea, depression) FDA-approved oral weight loss medications (orlistat, phentermine/topiramate ER, naltrexone/bupropion) as alternatives to injectables (note: phentermine monotherapy is approved for short-term use only) Patients should maintain realistic expectationsweight loss may be slower with hypothyroidism, even when well-controlled

This blog covers a recent Renegade Research Roundtable, two studies reporting on the effects of GLP-1 agonists on people with mast cell activation syndrome (MCAS) and intracranial hypertension, and two major GLP-1 long-COVID trials getting underway

Timing Your Injections Around Fasting Windows Injection timing relative to fasting windows affects both efficacy and tolerability

Many of the drugs we use in cardiovascular medicine have a much lower impact, so if this is validated, its very clinically significant, says Dr
