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Because these meds dont have to abide by the same clear packaging and labeling requirements as their brand-name cousins (they can come in a variety of vials and pre-filled syringes in various concentrations), it may be easier to mess up their administration

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Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease

doi: 10.1080/00325481.2021.2002616

That is a fraction of what the mouse data would predict if the compound translated 1:1, but allometric scaling rarely works that cleanly and community doses are below the mouse-equivalent scale
