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When activated by SLU-PP-332, ERR increases mitochondrial biogenesis, enhances fat oxidation, and improves metabolic efficiencysimilar to endurance exercise training
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The study did not find clear increases in risk for suicidal behaviors associated with the GLP-1-RA class of medications among older adults when compared with SGLT2i or DPP4i medications. However, Guo noted that the estimates were imprecise, and researchers could not rule out a modest increase in risk, so more research is necessary to further evaluate this potential risk

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