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2 Study Flow Diagram for Selecting Patients Initiating Glucagon-Like Peptide-1 Receptor Agonist (GLP-1RA) or Sodium-Glucose Cotransporter-2 Inhibitor (SGLT-2i)

Most common side effects: Nausea Vomiting Diarrhea Constipation Less common side effects Pancreatitis Inflammation of the pancreas, causing abdominal pain Gastroperesis The stopping or slowing of food moving out of the stomach Bowel obstruction A blockage that prevents food from passing through the intestines Gallstones Gallstone attacks and bile duct blockage Ozempic Face A hollowed look on the face, wrinkles on the face, and a change in the appearance of facial features as a result of rapid weight loss Source [7] GLP-1 medication statistics in the UK Statistics on GLP-1 medication usage in the UK are more limited than in the U.S

The ideal subject-reported outcome instrument would employ precise definitions for each symptom and their degree of severity, provide reliable inter-interviewer reproducibility, and be sensitive to the detection of changes in symptoms following initiation of the drug and any subsequent dose changes

Cons: higher cash cost

Paulus WJ, Tschpe C (2013) A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

Initial consultations and follow-up assessments occur via secure video or phone, and prescription refills are handled automatically