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In theory, this could counterbalance any insulin resistance from tesamorelin GH elevation

However, the -helical extension in TM1 of GIPR provides additional residues for tirzepatide recognition including one hydrogen bond (Y10 P and Q138 1.40b ) and a stacking interaction (K16 P and F127 1.29b )

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Only need to increase lean muscle mass: CJC-1295/Ipamorelin is more targeted for that goal and may be a better fit