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Vagal afferent GLP-1 receptor knockdown accelerates gastric emptying [518] and vagal afferent denervation [795] or peripheral administration of exendin (939) [794,795] blocks the effect of centrally or peripherally administered GLP-1 on gastric emptying

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Lancet 2019;394:121-30.PubMed 18

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When people lose weight on the drug they also lose fat cells, which can contain hormones, like estrogen that are part of regulating a woman's monthly cycle - including the intensity of cramps