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The search strategy targeted studies involving GLP-1 receptor agonists (e.g., exenatide, liraglutide, dulaglutide, lixisenatide, benaglutide, loxenatide, semaglutide) and multi-target receptor agonists (e.g., tirzepatide), focusing on gastrointestinal adverse events (e.g., nausea, vomiting, diarrhea, constipation, dyspepsia, and reduced appetite) in patients with type 2 diabetes mellitus (T2DM) (Supplementary Material)

Consider switching to a non-oral contraceptive method (such as an IUD, patch, or implant), or use an additional barrier method (such as condoms) for at least 4 weeks after starting semaglutide and for at least 4 weeks after each dose increase

Scand J Lab Invest

Switching to fresh medication often restarts progress that seemed to have plateaued