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This means roughly 50% of the drug clears every week after injection

However, if it improves your adherence and tolerability, the theoretical pharmacokinetic disadvantage may not matter practically

Blood sugar regulation improves through multiple pathways

The REWIND trial with dulaglutide and SUSTAIN-6 with semaglutide also demonstrated cardiovascular benefits

Compounded GLP-1 medications can be obtained through telehealth platforms that include a clinician evaluation and prescription process
