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El Eid L, Reynolds CA, Tomas A, et al

Obesity is the biggest risk factor for Type 2 diabetes, and substantial weight loss can help in reversal and remission of the disease, as well as reduced risk for conditions like high blood pressure, dyslipidemia, heart disease, and stroke

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Novo Nordisk/Septerna (May 2025) Novo committed $2.2B to partner with Septerna (US startup) on an oral obesity drug candidate ( [30] )

Chaudhari DD, Singh R, Mallappa RH, Rokana N, Kaushik JK, Bajaj R, et al

The rate of weight loss on Semaglutide can vary depending on several individual factors including a patients starting weight, participation, and adherence to treatment, and lifestyle changes