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JAMA - J Am Med Assoc (2015) 314(7):68799

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Tirzepatide (Mounjaro): Also once weekly, despite its dual action on GLP-1 and GIP receptors
The anti-AS effects of GLP-1RAs include the regulation of inflammation (109), reduction of intima-media thickening (120), improvement of blood lipid profile (121), and regulation of endothelial dysfunction (122)

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If everything goes well, ASC35 could be in registrational trials by 2028 and have a chance at approval by 2030 or 2031
