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This article thoroughly traces the developmental milestones of GLP-1 drugs, from their initial discovery to their clinical application, detailing the evolution of diverse GLP-1 medications along with their distinct pharmacological properties

Risk of bias was assessed using an adapted Quality Assessment Tool for In Vitro Studies (QUIN) tool

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A recently published, randomized, placebo-controlled trial found a greater reduction in BMI z-score (0.22 SDs) in adolescents receiving liraglutide compared with placebo

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