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Diabetes Care 41(2):356363 Karg MV, Bosch A, Kannenkeril D, Striepe K, Ott C, Schneider MP et al (2018) SGLT-2-inhibition with dapagliflozin reduces tissue sodium content: a randomised controlled trial

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doi: 10.1007/s13300-019-00733-9

metformin, sulfonylureas, TZDs, etc.) address only one of the underlying pathophysiology - lowering postprandial glucose levels, but their safety profiles and side effects, such as weight gain and hypoglycemia, may present challenges and limitations in their clinical use