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Both peptides activate intracellular signalling cascades through G-protein coupled receptors (GPCRs), primarily coupling through Gs proteins to increase cyclic AMP (cAMP) and activate protein kinase A (PKA)

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This GLP-1 receptor agonist mimics a hormone that controls hunger and blood sugar, helping patients lose an average of 15% of body weight over 68 weeks in clinical trials

Mounjaro activates two hormone receptors (GIP and GLP-1) while Wegovy targets only one (GLP-1)

Your answer can open the Compare Tool in a pricing context, where you can still sort by first-month price, average monthly cost, medication category, state availability, insurance support, and whether a program looks bundled or membership-plus-medication

It is also the maximum approved dose for pediatric patients in the eligible age group