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This 16-amino acid peptide, encoded by mitochondrial DNA, functions as a crucial signaling molecule between mitochondria and the cell nucleus, with wide-ranging effects on cellular metabolism and stress resistance

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The advent of incretin mimetics such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) has enriched the armamentarium for diabetes management owing to their glycaemic as well as extra-glycaemic benefits
