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Treatment with GLP1 Receptor Agonists Reduce Serum CRP Concentrations in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Gastric emptying was evaluated by measuring paracetamol absorption following a standardized breakfast

Conventional homology-directed repair (HDR) is widely recognized as the most effective knock-in method for treading monogenic diseases

Discussion In this study, leveraging non-viral LNPs and the HITI-mediated genome editing method, we engineered a secretion-enabled Exe4 peptide, scExe4, and developed an in vivo scExe4 peptide production reservoir via knock-in into mouse liver cells

The beta-cell specific transcription factor Nkx6.1 inhibits glucagon gene transcription by interfering with Pax6

Disproportionality analysis A sequential approach was adopted to systematically address major confounders: (1) An exploratory disproportionality approach comparing GLP-1RAs with all other drugs reported in the FAERS database, using venlafaxine as the positive control and empagliflozin/orlistat as the negative control