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Most people adjust within 12 weeks after starting semaglutide or increasing the dose
[DOI] [PubMed] [Google Scholar] 246.Xu E, Kumar M, Zhang Y, Ju W, Obata T, Zhang N, Liu S, Wendt A, Deng S, Ebina Y, Wheeler MB, Braun M, Wang Q

Jennifer La Grassa (new window) CBC News

Medications Help, But They Arent the Whole Solution Weight loss medications like semaglutides and tirzepatide can help suppress appetite and control blood sugar, leading to significant weight loss for patients

One study found that 90% of individuals experienced adverse side effects in the first eight weeks of treatment, while another study found that 70% of diabetes patients discontinued use after 2 years due to feeling chronically sick