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However, as more people have been prescribed Ozempic, those side effects have been eclipsed by concerns that the drug may cause certain users to experience stomach paralysis and other severe gastrointestinal problems
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Remarkably, there is evidence that GLP-1 agonists can enhance left ventricular ejection fraction, inotropy, coronary blood flow, cardiac output, and vascular endothelial function because of their cardiovascular effects and decrease overall cardiovascular event risks

For many people with type 2 diabetes, it is a struggle to achieve both A1C control and weight loss, since obesity has historically been harder to treat for those with type 2 diabetes, said Kenneth Custer, executive vice president and president of Lilly Cardiometabolic Health

Liraglutide 3 mg/day resulted in a median weight loss of 9.7%, whereas WR was 1.8% in the placebo group at the end of 56 weeks [48]
Semaglutide carries contraindications (personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, pregnancy), and dose adjustments are essential in kidney or liver impairment
