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Safety and Tolerability Across included studies, gastrointestinal intolerance was the most commonly reported adverseevent domain, consistent with the established incretin class profile [9, 10, 11, 12, 13, 14, 15, 16]

That 2% difference might sound small, but it represents a meaningful increase in risk that becomes more significant when you factor in the broader category of gastrointestinal side effects

Whenever significant weight loss occurs, some muscle loss can happen alongside fat loss

Understanding Covid-19 [Preprint] Villarreal-Caldern JR, et al