alternatives to glp 1 drugs A new FDA-approved obesity pill could offer a lower-cost alternative injectable GLP-1 like Ozempic and Mounjaro. In a major clinical trial, people taking the highest dose lost about 11% of GLP-1 Medications for Weight Loss:

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October 2, 2023

Its front-and-center in a lot of employees lives. Access bonus Workspan Daily Plus+ content on this subject: Increasing Demand Poses Expensive Deliberations Among the nearly 300 employers surveyed by the IFEBP for a recent study, 34% are now covering GLP-1 drugs for both diabetes management and weight loss, up 8 percentage points from 12 months ago

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Nausea is a side effect which affects 3050% of patients taking GLP-1R agonists at clinically licensed doses 15 , with higher doses glycemically more effective but consistently associated with unacceptable tolerability 16,17,18,19

All three amylin products appear to have the potential to challenge tirzepatide on an efficacy/tolerability basis, so it will be interesting to see how Novo Nordisk and Eli Lilly position these products alongside their current GLP-1 offerings