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Retatrutide showing promise in obesity (and type 2 diabetes)

Right now, GLP-1 for weight loss is very promising

GLP-1 acts on the GLP-1R, activating multiple intracellular signaling pathways, including the cAMP/PKA pathway, the PI3K/Akt signaling pathway, and pathways related to anti-inflammatory and anti-oxidative stress responses, among others

1 Its endogenous ligand is GLP-2 (GLP-2(133)), a member of the glucagon-like peptide family that also includes GLP-1 and glucagon
